Background: Parkinsonism is a common side-effect of antipsychotic drugs especially in older adults, who also present with a higher frequency of
Twenty-one patients with Parkinson's disease and psychosis were included in an open-label 8-week trial of olanzapine
This article sheds light on the case of a 22-year-old patient with paranoid schizophrenia
Parkinsonism usually appears days to weeks after starting antipsychotics, but in rare cases the onset delay may be several months or more
Psychotic symptoms are a common complication in Parkinson's
6 Olanzapine is also indicated, in combination with lithium or valproate for the short-term treatment of acute
No dosage adjustment of lithium or valproate is required when used in combination with olanzapine
large, flat, blue, or purplish patches in the skin
typical antipsychotics
Note: If an antipsychotic that blocks dopamine receptors needs to be used, atypical antipsychotics are better choices than typical antipsychotics
Olanzapine precautions
Samidorphan is an opioid antagonist
BACKGROUND Hallucinosis is a dopaminergic dose limiting complication of the treatment of idiopathic Parkinson’s disease
This includes information on what the medication is for, how to take it, possible side effects and safety information
Extrapyramidal symptoms are well-known side-effects of dopamine 2 receptor (D2R) antagonist drugs, which act on D2Rs in the striatum and mesocortex [], and comprise a range of acute and tardive motor phenomena, from rigidity, tremor and bradykinesia, to dystonia, dyskinesias, and akathisia
Includes OLANZapine indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more
Olanzapine is a prescription medication that treats bipolar disorder and schizophrenia
A treatment regimen of olanzapine (an atypical antipsychotic) of 15 mg/day was initiated for the patient and it was associated with extrapyramidal symptoms (EPS) such as drug-induced parkinsonism (DIP) and akathisia
Drowsiness, dizziness, lightheadedness, stomach upset, dry mouth, constipation, increased appetite, or weight gain may occur
Olanzapine is well absorbed and reaches peak concentrations in approximately 6 hours following an oral dose